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2019 | 1 |
2020 | 2 |
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Page 1
Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab.
Nat Cancer. 2020 Sep;1(9):873-881. doi: 10.1038/s43018-020-0096-5. Epub 2020 Aug 3.
Nat Cancer. 2020.
PMID: 35121950
Coenzyme A fuels T cell anti-tumor immunity.
St Paul M, Saibil SD, Han S, Israni-Winger K, Lien SC, Laister RC, Sayad A, Penny S, Amaria RN, Haydu LE, Garcia-Batres CR, Kates M, Mulder DT, Robert-Tissot C, Gold MJ, Tran CW, Elford AR, Nguyen LT, Pugh TJ, Pinto DM, Wargo JA, Ohashi PS.
St Paul M, et al. Among authors: lien sc.
Cell Metab. 2021 Dec 7;33(12):2415-2427.e6. doi: 10.1016/j.cmet.2021.11.010.
Cell Metab. 2021.
PMID: 34879240
Free article.
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Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.
Cindy Yang SY, Lien SC, Wang BX, Clouthier DL, Hanna Y, Cirlan I, Zhu K, Bruce JP, El Ghamrasni S, Iafolla MAJ, Oliva M, Hansen AR, Spreafico A, Bedard PL, Lheureux S, Razak A, Speers V, Berman HK, Aleshin A, Haibe-Kains B, Brooks DG, McGaha TL, Butler MO, Bratman SV, Ohashi PS, Siu LL, Pugh TJ.
Cindy Yang SY, et al. Among authors: lien sc.
Nat Commun. 2021 Aug 26;12(1):5137. doi: 10.1038/s41467-021-25432-7.
Nat Commun. 2021.
PMID: 34446728
Free PMC article.
Clinical Trial.
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Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy.
St Paul M, Saibil SD, Kates M, Han S, Lien SC, Laister RC, Hezaveh K, Kloetgen A, Penny S, Guo T, Garcia-Batres C, Smith LK, Chung DC, Elford AR, Sayad A, Pinto D, Mak TW, Hirano N, McGaha T, Ohashi PS.
St Paul M, et al. Among authors: lien sc.
Cell Rep Med. 2024 Mar 19;5(3):101465. doi: 10.1016/j.xcrm.2024.101465. Epub 2024 Mar 8.
Cell Rep Med. 2024.
PMID: 38460518
Free PMC article.
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Tumor reactive γδ T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient.
Lien SC, Ly D, Yang SYC, Wang BX, Clouthier DL, St Paul M, Gadalla R, Noamani B, Garcia-Batres CR, Boross-Harmer S, Bedard PL, Pugh TJ, Spreafico A, Hirano N, Razak ARA, Ohashi PS.
Lien SC, et al.
Nat Commun. 2024 Feb 6;15(1):1094. doi: 10.1038/s41467-024-45449-y.
Nat Commun. 2024.
PMID: 38321065
Free PMC article.
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IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function.
St Paul M, Saibil SD, Lien SC, Han S, Sayad A, Mulder DT, Garcia-Batres CR, Elford AR, Israni-Winger K, Robert-Tissot C, Zon M, Katz SR, Shaw PA, Clarke BA, Bernardini MQ, Nguyen LT, Haibe-Kains B, Pugh TJ, Ohashi PS.
St Paul M, et al. Among authors: lien sc.
Cancer Immunol Res. 2020 Mar;8(3):321-333. doi: 10.1158/2326-6066.CIR-19-0521. Epub 2020 Jan 21.
Cancer Immunol Res. 2020.
PMID: 31964625
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An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE).
Clouthier DL, Lien SC, Yang SYC, Nguyen LT, Manem VSK, Gray D, Ryczko M, Razak ARA, Lewin J, Lheureux S, Colombo I, Bedard PL, Cescon D, Spreafico A, Butler MO, Hansen AR, Jang RW, Ghai S, Weinreb I, Sotov V, Gadalla R, Noamani B, Guo M, Elston S, Giesler A, Hakgor S, Jiang H, McGaha T, Brooks DG, Haibe-Kains B, Pugh TJ, Ohashi PS, Siu LL.
Clouthier DL, et al. Among authors: lien sc.
J Immunother Cancer. 2019 Mar 13;7(1):72. doi: 10.1186/s40425-019-0541-0.
J Immunother Cancer. 2019.
PMID: 30867072
Free PMC article.
Clinical Trial.
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